Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 15/20 | 0.57 |
| ▸ | CDK2 | P24941 | 6/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670103 | 0.95 | GSK3B (0.56) | GSK3BCDK2CCNE1 | |
| SCHEMBL24669688 | 0.83 | GSK3B (0.53) | GSK3BCDK2CCNE1 | |
| SCHEMBL24667992 | 0.78 | GSK3B (0.48) | GSK3BCDK2CCNE1 | |
| SCHEMBL13122798 | 0.76 | GSK3B (0.68) | GSK3BCDK2CCNE1 | |
| SCHEMBL13289819 | 0.76 | GSK3B (0.52) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954115 | 0.76 | GSK3B (0.52) | GSK3BCDK2CCNE1 | |
| SCHEMBL24670105 | 0.74 | GSK3B (0.47) | GSK3BCDK2CCNE1 | |
| SCHEMBL13122702 | 0.74 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL13290022 | 0.74 | GSK3B (0.54) | GSK3BCDK2CCNE1 | |
| SCHEMBL12953029 | 0.73 | GSK3B (1.00) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |