Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22790200 | 0.84 | PPARG (0.43) | GPBAR1KMT2ARAB9APPARGPPARD | |
| SCHEMBL2467011 | 0.83 | GPBAR1 (0.47) | GPBAR1KMT2ARAB9APPARGPPARD | |
| SCHEMBL29397419 | 0.83 | GPBAR1 (0.47) | GPBAR1KMT2ARAB9APPARGPPARD | |
| SCHEMBL27574042 | 0.82 | GPBAR1 (0.46) | GPBAR1PPARGPPARDPPARANR1H4 | |
| SCHEMBL28600495 | 0.79 | GPBAR1 (0.44) | GPBAR1PPARGPPARDPPARANR1H4 | |
| SCHEMBL28143152 | 0.74 | STAT3 (0.42) | ALOX5APFEN1KMT2ARAB9ATSHR | |
| SCHEMBL1902229 | 0.74 | ALOX5AP (0.35) | ALOX5APFEN1KMT2ARAB9AACHE | |
| SCHEMBL19738519 | 0.72 | KCNH2 (0.38) | NR1H4 | |
| SCHEMBL28143153 | 0.72 | KMT2A (0.42) | GPBAR1ALOX5APFEN1KMT2ARAB9A | |
| SCHEMBL22790240 | 0.70 | GPBAR1 (0.41) | GPBAR1KMT2ARAB9APPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772199-B2 | Herbicidal compositions for tolerant or resistant maize crops | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-08 | — | — | US | disclosed |
| US-20110224077-A1 | Herbicidal Compositions for Tolerant or Resistant Maize Crops | BAYER CORPSCIENCE AG (DE) | 2011-09-15 | — | — | US | disclosed |
| US-7012040-B2 | Glufosinates, glyphosates, imidazolinones, azoles of protoporphyrinogen oxidase inhibitors, cyclohexanediones, heteroaryloxyphenoxypropionic acids, and foliar- and soil-acting hebicides against mono- and di-cotyledonous | HOECHST SCHERING AGREVO GMBH (DE) | 2006-03-14 | — | — | US | disclosed |
| US-20020094934-A1 | Glufosinates, glyphosates, imidazolinones, azoles of protoporphyrinogen oxidase inhibitors, cyclohexanediones, heteroaryloxyphenoxypropionic acids, and foliar- and soil-acting hebicides against mono- and di-cotyledonous | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224077-A1 | Herbicidal Compositions for Tolerant or Resistant Maize Crops | PPOX, PNPO, DDO | GPBAR1 2286/4885ALOX5AP 1628/4885FEN1 1573/4885 |
| US-20020094934-A1 | Glufosinates, glyphosates, imidazolinones, azoles of protoporphyrinogen oxidase inhibitors, cyclohexanediones, heteroaryloxyphenoxypropionic acids, and foliar- and soil-acting hebicides against mono- and di-cotyledonous | PPOX, DDO, PNPO | GPBAR1 1550/4885ALOX5AP 2986/4885FEN1 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.