Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803469 | 1.00 | NAMPT (0.44) | NAMPTTMPRSS2NPC1RAB9AKDM4E | |
| SCHEMBL29803348 | 0.97 | NAMPT (0.46) | NAMPTTMPRSS2 | |
| SCHEMBL24670218 | 0.96 | NAMPT (0.46) | NAMPTTMPRSS2 | |
| SCHEMBL24670217 | 0.96 | NAMPT (0.46) | NAMPTTMPRSS2 | |
| SCHEMBL29803623 | 0.92 | NAMPT (0.47) | NAMPTTMPRSS2NPC1RAB9AKDM4E | |
| SCHEMBL29803599 | 0.89 | NAMPT (0.41) | NAMPTKDM4EPRMT5WDR77 | |
| SCHEMBL24670614 | 0.89 | NAMPT (0.40) | NAMPTTMPRSS2PRMT5WDR77 | |
| SCHEMBL24891728 | 0.88 | NAMPT (0.46) | NAMPTNPC1RAB9AKDM4E | |
| SCHEMBL24670876 | 0.88 | NAMPT (0.41) | NAMPTTMPRSS2 | |
| SCHEMBL24669413 | 0.88 | NAMPT (0.49) | NAMPTTMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |