SCHEMBL24670876

SCHEMBL24670876

Cc1cc(C2=CCN(/C(=N\C(=O)OC(C)(C)C)N(C)C(=O)OC(C)(C)C)CC2)ccc1C(=O)Nc1ccc2c(c1)CN(/C(=N\C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)C2

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 19/20 0.41
TMPRSS2 O15393 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24670217 0.92 NAMPT (0.46) NAMPTTMPRSS2
SCHEMBL24670218 0.92 NAMPT (0.46) NAMPTTMPRSS2
SCHEMBL29803469 0.88 NAMPT (0.44) NAMPTTMPRSS2
SCHEMBL29803348 0.88 NAMPT (0.46) NAMPTTMPRSS2
SCHEMBL24670210 0.88 NAMPT (0.44) NAMPTTMPRSS2
SCHEMBL24669413 0.84 NAMPT (0.49) NAMPTTMPRSS2
SCHEMBL30182412 0.83 NAMPT (0.51) NAMPTTMPRSS2
SCHEMBL24891742 0.83 NAMPT (0.51) NAMPTTMPRSS2
SCHEMBL29803599 0.82 NAMPT (0.41) NAMPT
SCHEMBL24670614 0.82 NAMPT (0.40) NAMPTTMPRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022192162-A1 NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2022-09-15 WO disclosed