Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822575 | 0.69 | TOP2A (0.31) | TOP2A | |
| SCHEMBL12616367 | 0.63 | TOP2A (0.37) | TOP2A | |
| SCHEMBL20283109 | 0.63 | TOP2A (0.37) | TOP2A | |
| SCHEMBL18237766 | 0.62 | ADORA2A (0.43) | — | |
| SCHEMBL1102015 | 0.61 | — | — | |
| SCHEMBL29357583 | 0.61 | ADORA2A (0.36) | — | |
| SCHEMBL138622 | 0.61 | ADORA2A (0.36) | — | |
| SCHEMBL24210738 | 0.61 | USP2 (0.38) | TOP2A | |
| SCHEMBL23119748 | 0.60 | ADORA2B (0.44) | — | |
| SCHEMBL15423531 | 0.59 | ADORA2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |