Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669613 | 1.00 | NPY2R (0.38) | NPY2RCHRM1NAMPTHTTL3MBTL1 | |
| SCHEMBL24669610 | 1.00 | NPY2R (0.38) | NPY2RCHRM1NAMPTHTTL3MBTL1 | |
| SCHEMBL24670254 | 1.00 | NPY2R (0.38) | NPY2RCHRM1NAMPTHTTL3MBTL1 | |
| SCHEMBL29803600 | 0.94 | NPC1 (0.38) | NPY2RCHRM1NAMPTMAPTMAPK1 | |
| SCHEMBL24670287 | 0.94 | CHRM1 (0.44) | NPY2RCHRM1HTTL3MBTL1MAPT | |
| SCHEMBL24670289 | 0.94 | CHRM1 (0.44) | NPY2RCHRM1HTTL3MBTL1MAPT | |
| SCHEMBL29803193 | 0.94 | NAMPT (0.40) | CHRM1NAMPTMAPTWDR5SCN9A | |
| SCHEMBL24671296 | 0.94 | MAPT (0.37) | NPY2RCHRM1NAMPTHTTL3MBTL1 | |
| SCHEMBL24671294 | 0.94 | MAPT (0.37) | NPY2RCHRM1NAMPTHTTL3MBTL1 | |
| SCHEMBL24671547 | 0.92 | NPY2R (0.37) | NPY2RCHRM1NAMPTHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |