Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 3/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671294 | 1.00 | MAPT (0.37) | MAPTSMN1; SMN2TP53THRBNAMPT | |
| SCHEMBL24670254 | 0.94 | NPY2R (0.38) | MAPTSMN1; SMN2NAMPTNPY2RCHRM1 | |
| SCHEMBL24670258 | 0.94 | NPY2R (0.38) | MAPTSMN1; SMN2NAMPTNPY2RCHRM1 | |
| SCHEMBL24669613 | 0.94 | NPY2R (0.38) | MAPTSMN1; SMN2NAMPTNPY2RCHRM1 | |
| SCHEMBL24669610 | 0.94 | NPY2R (0.38) | MAPTSMN1; SMN2NAMPTNPY2RCHRM1 | |
| SCHEMBL24671182 | 0.93 | NAMPT (0.38) | MAPTSMN1; SMN2TP53THRBNAMPT | |
| SCHEMBL29803596 | 0.93 | NAMPT (0.38) | MAPTSMN1; SMN2TP53THRBNAMPT | |
| SCHEMBL24670287 | 0.90 | CHRM1 (0.44) | MAPTSMN1; SMN2NPY2RCHRM1NPC1 | |
| SCHEMBL24670289 | 0.90 | CHRM1 (0.44) | MAPTSMN1; SMN2NPY2RCHRM1NPC1 | |
| SCHEMBL29803600 | 0.90 | NPC1 (0.38) | MAPTTP53NAMPTNPY2RCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |