Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 5/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670915 | 0.92 | SCN9A (0.36) | SCN9APDK4NAMPTWDR5CDK9 | |
| SCHEMBL24671365 | 0.91 | SCN9A (0.34) | SCN9APDK4NAMPTWDR5CDK9 | |
| SCHEMBL24670930 | 0.90 | SCN9A (0.34) | SCN9APDK4NAMPTWDR5CDK9 | |
| SCHEMBL29803193 | 0.89 | NAMPT (0.40) | SCN9APDK4NAMPTWDR5CDK9 | |
| SCHEMBL24670834 | 0.88 | WDR5 (0.38) | SCN9APDK4NAMPTWDR5CDK9 | |
| SCHEMBL24669446 | 0.88 | NAMPT (0.46) | NAMPT | |
| SCHEMBL29803306 | 0.88 | WDR5 (0.38) | SCN9APDK4NAMPTWDR5CDK9 | |
| SCHEMBL24669451 | 0.88 | NAMPT (0.46) | NAMPT | |
| SCHEMBL24670835 | 0.88 | WDR5 (0.38) | SCN9APDK4NAMPTWDR5CDK9 | |
| SCHEMBL24671375 | 0.87 | WDR5 (0.36) | SCN9APDK4NAMPTWDR5CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |