Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.50 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | LIPC | P11150 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 5/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803379 | 0.88 | NAMPT (0.55) | NAMPTWNT3ALIPCLIPGKIT | |
| SCHEMBL24671383 | 0.85 | NAMPT (0.40) | NAMPTWNT3AMCHR1CCNT1CDK9 | |
| SCHEMBL24671384 | 0.85 | NAMPT (0.40) | NAMPTWNT3AMCHR1CCNT1CDK9 | |
| SCHEMBL24891933 | 0.84 | NAMPT (0.55) | NAMPTWNT3ALIPCLIPGKIT | |
| SCHEMBL24892373 | 0.84 | NAMPT (0.55) | NAMPTWNT3ALIPCLIPGKIT | |
| SCHEMBL29803362 | 0.84 | NAMPT (0.48) | NAMPTWNT3AKITMCHR1GRM5 | |
| SCHEMBL24671267 | 0.83 | NAMPT (0.49) | NAMPTWNT3ALIPCLIPGKIT | |
| SCHEMBL24669471 | 0.82 | NAMPT (0.53) | NAMPTWNT3ATLR7CDK7CDK13 | |
| SCHEMBL24670609 | 0.81 | NAMPT (0.52) | NAMPTWNT3ATLR7CDK7CDK13 | |
| SCHEMBL29803508 | 0.81 | NAMPT (0.52) | NAMPTWNT3ATLR7CDK7CDK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |