Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 3/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671070 | 0.92 | NAMPT (0.50) | NAMPTWNT3ALIPCLIPGKIT | |
| SCHEMBL24669223 | 0.88 | NAMPT (0.61) | NAMPTWNT3ALIPCLIPGKIT | |
| SCHEMBL29803379 | 0.87 | NAMPT (0.55) | NAMPTWNT3ALIPCLIPGKIT | |
| SCHEMBL24670448 | 0.84 | NAMPT (0.40) | NAMPTWNT3APTGER4DRD2 | |
| SCHEMBL29803216 | 0.84 | NAMPT (0.40) | NAMPTWNT3APTGER4DRD2 | |
| SCHEMBL24670472 | 0.84 | NAMPT (0.49) | NAMPTWNT3AKITGPR119PDK4 | |
| SCHEMBL24670296 | 0.83 | NAMPT (0.50) | NAMPTWNT3ALIPCLIPGPTGER4 | |
| SCHEMBL24892373 | 0.83 | NAMPT (0.55) | NAMPTWNT3ALIPCLIPGPTGER4 | |
| SCHEMBL24891933 | 0.83 | NAMPT (0.55) | NAMPTWNT3ALIPCLIPGPTGER4 | |
| SCHEMBL29803791 | 0.83 | NAMPT (0.38) | NAMPTWNT3APTGER4KITDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |