Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.39 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL29803721 | 0.99 | NAMPT (0.48) | NAMPTKITWNT3ASMN1; SMN2MEN1 | |
| SCHEMBL24670460 | 0.91 | NAMPT (0.49) | NAMPTKITWNT3AMAPTTDP1 | |
| SCHEMBL24892276 | 0.85 | NAMPT (0.57) | NAMPTKITWNT3ASMN1; SMN2MEN1 | |
| SCHEMBL24670226 | 0.85 | NAMPT (0.57) | NAMPTKITWNT3ASMN1; SMN2MEN1 | |
| SCHEMBL24670346 | 0.83 | NAMPT (0.48) | NAMPTKITWNT3ASMN1; SMN2MEN1 | |
| SCHEMBL30182548 | 0.82 | NAMPT (0.54) | NAMPTKITWNT3ASMN1; SMN2MEN1 | |
| SCHEMBL24670345 | 0.82 | NAMPT (0.40) | NAMPTKITWNT3AMEN1KMT2A | |
| SCHEMBL24891783 | 0.82 | NAMPT (0.57) | NAMPTKITWNT3ASMN1; SMN2MEN1 | |
| SCHEMBL24891670 | 0.82 | NAMPT (0.57) | NAMPTKITWNT3ASMN1; SMN2MEN1 | |
| SCHEMBL24891842 | 0.81 | NAMPT (0.45) | NAMPTKITWNT3ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |