Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.57 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | FPR3 | P25089 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.42 |
| ▸ | LIPC | P11150 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891865 | 0.96 | NAMPT (0.55) | NAMPTWNT3AKITCDK7CDK13 | |
| SCHEMBL24891670 | 0.94 | NAMPT (0.57) | NAMPTWNT3AKITCDK7CDK13 | |
| SCHEMBL24892192 | 0.92 | NAMPT (0.51) | NAMPTWNT3AKITCDK7CDK13 | |
| SCHEMBL24892373 | 0.91 | NAMPT (0.55) | NAMPTWNT3AKITCDK7CDK13 | |
| SCHEMBL24891722 | 0.90 | NAMPT (0.63) | NAMPTWNT3AKITCDK7CDK13 | |
| SCHEMBL24670226 | 0.89 | NAMPT (0.57) | NAMPTWNT3AKITCDK7CDK13 | |
| SCHEMBL24892276 | 0.89 | NAMPT (0.57) | NAMPTWNT3AKITCDK7CDK13 | |
| SCHEMBL24891878 | 0.89 | NAMPT (0.51) | NAMPTWNT3AKITCDK7CDK13 | |
| SCHEMBL24891972 | 0.88 | NAMPT (0.51) | NAMPTWNT3AKITCDK7CDK13 | |
| SCHEMBL30182359 | 0.88 | NAMPT (0.51) | NAMPTWNT3AKITCDK7CDK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |