Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803203 | 1.00 | GRM4 (0.60) | GRM4KMT2ASTAT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24670582 | 0.81 | KMT2A (0.57) | GRM4KMT2ASTAT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29803339 | 0.81 | KMT2A (0.57) | GRM4KMT2ASTAT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24671458 | 0.79 | ABCB1 (0.63) | GRM4KMT2ASTAT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24670490 | 0.79 | MAOB (0.49) | KMT2AALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29803308 | 0.79 | MAOB (0.49) | KMT2AALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL879728 | 0.76 | GRM4 (0.59) | GRM4KMT2ASTAT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15972268 | 0.76 | GRM4 (0.59) | GRM4KMT2ASTAT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30159535 | 0.76 | GRM4 (0.59) | GRM4KMT2ASTAT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19661750 | 0.75 | GRM4 (0.58) | GRM4KMT2ASTAT1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |