Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803566 | 1.00 | NAMPT (0.38) | NAMPTMAPTLMNAHTTMEN1 | |
| SCHEMBL24669251 | 1.00 | NAMPT (0.38) | NAMPTMAPTLMNAHTTMEN1 | |
| SCHEMBL24670493 | 0.91 | NAMPT (0.46) | NAMPTWNT3A | |
| SCHEMBL24670496 | 0.91 | NAMPT (0.46) | NAMPTWNT3A | |
| SCHEMBL24669853 | 0.90 | NAMPT (0.36) | NAMPTMAPTALDH1A1CDK9WNT3A | |
| SCHEMBL24669851 | 0.90 | NAMPT (0.36) | NAMPTMAPTALDH1A1CDK9WNT3A | |
| SCHEMBL29803459 | 0.87 | MAPKAPK2 (0.36) | NAMPTMAPTLMNAHTTMEN1 | |
| SCHEMBL29803193 | 0.87 | NAMPT (0.40) | NAMPTMAPTWDR5TRPV1JAK1 | |
| SCHEMBL24670949 | 0.87 | NAMPT (0.41) | NAMPTMAPTLMNAHTTALDH1A1 | |
| SCHEMBL24670952 | 0.87 | NAMPT (0.41) | NAMPTMAPTLMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |