Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 3/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670949 | 1.00 | NAMPT (0.41) | NAMPTCCNT1CDK9WDR5PRMT5 | |
| SCHEMBL24671356 | 0.94 | NAMPT (0.40) | NAMPTWDR5PRMT5WDR77MAPT | |
| SCHEMBL29803446 | 0.94 | NAMPT (0.40) | NAMPTWDR5PRMT5WDR77MAPT | |
| SCHEMBL24671289 | 0.94 | NAMPT (0.40) | NAMPTWDR5PRMT5WDR77MAPT | |
| SCHEMBL29803520 | 0.93 | NAMPT (0.39) | NAMPTCCNT1CDK9WDR5PRMT5 | |
| SCHEMBL29803351 | 0.93 | NAMPT (0.39) | NAMPTCCNT1CDK9WDR5PRMT5 | |
| SCHEMBL24670300 | 0.93 | NAMPT (0.39) | NAMPTCCNT1CDK9WDR5PRMT5 | |
| SCHEMBL24669509 | 0.93 | NAMPT (0.39) | NAMPTCCNT1CDK9WDR5PRMT5 | |
| SCHEMBL24670307 | 0.93 | WDR5 (0.41) | NAMPTWDR5 | |
| SCHEMBL24671257 | 0.93 | NAMPT (0.39) | NAMPTCCNT1CDK9PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |