SCHEMBL2467050

SCHEMBL2467050

C=Cc1ccccc1-c1ccc(-c2ccccc2C=C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
GRIN2D O15399 2/20 0.38
GRIN3B O60391 2/20 0.38
GRIN1 Q05586 2/20 0.38
GRIN2A Q12879 2/20 0.38
GRIN2B Q13224 2/20 0.38
GRIN2C Q14957 2/20 0.38
GRIN3A Q8TCU5 2/20 0.38
FLT3 P36888 2/20 0.38
XDH P47989 1/20 0.38
TSHR P16473 1/20 0.38
ATR Q13535 1/20 0.35
HSD17B10 Q99714 2/20 0.33
HPGD P15428 1/20 0.33
BCL2L1 Q07817 1/20 0.33
DRD1 P21728 1/20 0.33
PTGER1 P34995 1/20 0.33
PTGER3 P43115 1/20 0.33
PTGER2 P43116 1/20 0.33
ABL1 P00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8758641 0.93 ALDH1A1 (0.43) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL76904 0.92 ALDH1A1 (0.46) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29418124 0.92 ALDH1A1 (0.46) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL585316 0.91 ALDH1A1 (0.48) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6320053 0.91 ALDH1A1 (0.41) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL28372677 0.90 ALDH1A1 (0.44) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
Biphenyl SCHEMBL28948287 0.90 ALDH1A1 (0.44) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL32662830 0.90 FLT3 (0.47) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL30485479 0.90 ALDH1A1 (0.44) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
Water SCHEMBL8470277 0.90 ALDH1A1 (0.44) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10119014-B2 Rubber composition for tires, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2018-11-06 US disclosed
EP-2770021-B1 RUBBER COMPOSITION FOR TIRES, AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-09-28 EP disclosed
EP-2746332-B1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-07-20 EP disclosed
EP-2636700-B1 RUBBER COMPOSITION FOR TIRE AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-01-06 EP disclosed
US-9102816-B2 Tire rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-08-11 US disclosed
EP-2770021-A1 RUBBER COMPOSITION FOR TIRES, AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-08-27 EP disclosed
US-20140228500-A1 RUBBER COMPOSITION FOR TIRE, AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-08-14 US disclosed
US-20140213713-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-31 US disclosed
US-20140194552-A1 RUBBER COMPOSITION FOR TIRES, AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-10 US disclosed
EP-2746332-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-06-25 EP disclosed
EP-2746331-A1 RUBBER COMPOSITION FOR TIRE, AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-06-25 EP disclosed
US-8614272-B2 Tire rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-12-24 US disclosed
EP-2636700-A1 RUBBER COMPOSITION FOR TIRE AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2013-09-11 EP disclosed
US-20130172458-A1 RUBBER COMPOSITION FOR TIRE AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-07-04 US disclosed
US-20120277348-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-11-01 US disclosed
EP-2518104-A1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2012-10-31 EP disclosed
EP-2371580-B1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2012-10-17 EP disclosed
US-20110245370-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-10-06 US disclosed
EP-2371580-A1 Tire rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2011-10-05 EP disclosed