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Sugi Predict / Compounds / SCHEMBL2467065

SCHEMBL2467065

SCHEMBL2467065

CCCCOc1c(Cl)ccc(-c2cc(N)c(Cl)c(C(=O)O)n2)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5AP P20292 1/20 0.38
▸ FEN1 P39748 1/20 0.38
▸ CNR1 P21554 5/20 0.36
▸ THRA P10827 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ PTPN11 Q06124 4/20 0.34
▸ HTT P42858 1/20 0.34
▸ RECQL P46063 1/20 0.34
▸ PRKAB2 O43741 1/20 0.34
▸ PRKAG1 P54619 1/20 0.34
▸ PRKAA2 P54646 1/20 0.34
▸ PRKAA1 Q13131 1/20 0.34
▸ PRKAG3 Q9UGI9 1/20 0.34
▸ PRKAG2 Q9UGJ0 1/20 0.34
▸ PRKAB1 Q9Y478 1/20 0.34
▸ PPARD Q03181 1/20 0.34
▸ MCL1 Q07820 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ KCNH2 Q12809 1/20 0.33
▸ CACNA1C Q13936 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2463882 0.91 ALOX5AP (0.39) ALOX5APFEN1PRKAB2PRKAG1PRKAA2
SCHEMBL3326935 0.90 CNR1 (0.40) ALOX5APFEN1CNR1HTTRECQL
SCHEMBL3327374 0.89 ALOX5AP (0.38) ALOX5APFEN1PRKAB2PRKAG1PRKAA2
SCHEMBL2465297 0.87 ALOX5AP (0.38) ALOX5APFEN1PRKAB2PRKAG1PRKAA2
SCHEMBL115379 0.85 ALDH1A1 (0.40) ALOX5APFEN1PRKAB2PRKAG1PRKAA2
SCHEMBL29349463 0.85 ALDH1A1 (0.40) ALOX5APFEN1PRKAB2PRKAG1PRKAA2
SCHEMBL29405327 0.85 ALDH1A1 (0.40) ALOX5APFEN1PRKAB2PRKAG1PRKAA2
SCHEMBL2467067 0.85 FFAR4 (0.37) ALOX5APFEN1CNR1THRATHRB
SCHEMBL2465874 0.85 ALOX5AP (0.40) ALOX5APFEN1PRKAB2PRKAG1PRKAA2
Potassium SCHEMBL679681 0.84 ALDH1A1 (0.40) ALOX5APFEN1PRKAB2PRKAG1PRKAA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2060566-B1 Poly-substituted aryls DOW AGROSCIENCES LLC (US) 2016-06-08 — — EP claimed
EP-2060566-B1 Poly-substituted aryls DOW AGROSCIENCES LLC (US) 2016-06-08 — — EP disclosed
EP-2939540-A1 HERBICIDE SAFENER COMBINATION Bayer Intellectual Property GmbH (DE) 2015-11-04 — — EP disclosed
EP-2939541-A1 HERBICIDE SAFENER COMBINATION Bayer Intellectual Property GmbH (DE) 2015-11-04 — — EP disclosed
US-8962523-B2 Herbicide/safener combination BAYER CROPSCIENCE AG (DE) 2015-02-24 — — US disclosed
US-20150051074-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2015-02-19 — — US disclosed
CN-102731381-A 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC 2012-10-17 — — CN disclosed
CN-102731382-A 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC 2012-10-17 — — CN disclosed
CN-101360713-B 6- (polysubstituted aryl) -4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC 2012-08-15 — — CN disclosed
CN-102300459-A Herbicide-safener combination — 2011-12-28 — — CN disclosed
EP-1973881-B1 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2009-10-28 — — EP disclosed
EP-2060566-A1 Poly-substituted aryls Dow AgroSciences LLC (US) 2009-05-20 — — EP disclosed
US-7498468-B2 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2009-03-03 — — US disclosed
CN-101360713-A 6- (polysubstituted aryl) -4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2009-02-04 — — CN disclosed
EP-1973881-A2 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES Dow Agrosciences LLC (US) 2008-10-01 — — EP disclosed
US-20080051596-A1 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2008-02-28 — — US disclosed
US-20080045734-A1 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2008-02-21 — — US disclosed
US-7314849-B2 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides DOW AGROSCIENCES LLC (US) 2008-01-01 — — US disclosed
US-20070179060-A1 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides CORTEVA AGRISCIENCE LLC 2007-08-02 — — US disclosed
WO-2007082098-A2 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2007-07-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045734-A1 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides AAAS, DDT, AADAC ALOX5AP 1857/4885FEN1 4273/4885CNR1 2885/4885
US-20070179060-A1 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides AAAS, DDT, AADAC ALOX5AP 1857/4885FEN1 4273/4885CNR1 2885/4885
US-20080051596-A1 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides AAAS, DDT, AADAC ALOX5AP 1857/4885FEN1 4273/4885CNR1 2885/4885
US-20150051074-A1 HERBICIDE/SAFENER COMBINATION DDT, CYP2W1, GAP43 ALOX5AP 3496/4885FEN1 762/4885CNR1 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.