Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803585 | 1.00 | TMPRSS2 (0.54) | TMPRSS2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL29803740 | 0.93 | TMPRSS2 (0.57) | TMPRSS2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL24670713 | 0.93 | TMPRSS2 (0.57) | TMPRSS2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL30181059 | 0.90 | TMPRSS2 (0.48) | TMPRSS2MAPTLMNAHTR1DSLC6A4 | |
| SCHEMBL29802922 | 0.89 | TMPRSS2 (0.53) | TMPRSS2MAPTNPC1RAB9AHTR1D | |
| SCHEMBL29802915 | 0.89 | TMPRSS2 (0.49) | TMPRSS2MAPTLMNAHTR1DSLC6A4 | |
| SCHEMBL24671270 | 0.88 | TMPRSS2 (0.52) | TMPRSS2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL24670807 | 0.88 | TMPRSS2 (0.54) | TMPRSS2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL29803023 | 0.88 | TMPRSS2 (0.54) | TMPRSS2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL29803204 | 0.88 | TMPRSS2 (0.52) | TMPRSS2MAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |