Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891879 | 0.91 | MAPT (0.64) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL24669978 | 0.91 | MAPT (0.64) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| Trifluoroacetic Acid SCHEMBL30182790 | 0.83 | NPC1 (0.56) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL24892272 | 0.81 | NPC1 (0.63) | MAPTALDH1A1NPC1RAB9AUSP2 | |
| SCHEMBL30180770 | 0.81 | NPC1 (0.60) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL24891925 | 0.81 | NPC1 (0.60) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL24671380 | 0.81 | MAPT (0.53) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL24891910 | 0.81 | MAPT (0.53) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL29802966 | 0.81 | MAPT (0.55) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL29803013 | 0.81 | NPC1 (0.58) | MAPTALDH1A1CYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |