Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24667821 | 0.91 | TMPRSS2 (0.54) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL24669978 | 0.86 | MAPT (0.64) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL24891879 | 0.86 | MAPT (0.64) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL29802852 | 0.85 | NPC1 (0.44) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL24670306 | 0.84 | TMPRSS2 (0.43) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL24671336 | 0.84 | TMPRSS2 (0.52) | MAPTALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL24670508 | 0.84 | MAPT (0.44) | MAPTALDH1A1NPC1RAB9AUSP2 | |
| SCHEMBL24891899 | 0.84 | TMPRSS2 (0.47) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL29802928 | 0.83 | HDAC1 (0.40) | MAPTALDH1A1HPGDCYP2C19NPC1 | |
| SCHEMBL24669387 | 0.81 | TMPRSS2 (0.45) | MAPTALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |