SCHEMBL2467078

SCHEMBL2467078

C=C(CC(=O)COC(C)=O)C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.46
LMNA P02545 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TSHR P16473 2/20 0.40
MAPT P10636 2/20 0.38
GLO1 Q04760 1/20 0.37
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
THRB P10828 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
FAAH O00519 1/20 0.35
CYP2D6 P10635 2/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2470732 0.86 TSHR (0.40) ALDH1A1LMNAHSD17B10TSHRGAA
SCHEMBL2258666 0.84 ALDH1A1 (0.54) ALDH1A1LMNAHSD17B10TSHRMAPT
SCHEMBL272491 0.81 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TSHRMAPT
SCHEMBL7037635 0.78 ALDH1A1 (0.47) ALDH1A1LMNAHSD17B10TSHRMAPT
SCHEMBL8580106 0.78 ALDH1A1 (0.47) ALDH1A1LMNAHSD17B10TSHRMAPT
SCHEMBL561195 0.76 GAA (0.58) ALDH1A1LMNAHSD17B10TSHRMGAM
SCHEMBL2706963 0.75 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10TSHRMAPT
Methyl Alcohol SCHEMBL10632152 0.75 GAA (0.56) ALDH1A1LMNAHSD17B10TSHRMGAM
SCHEMBL60515 0.74 GAA (0.61) ALDH1A1LMNAHSD17B10TSHRMAPT
SCHEMBL262250 0.74 EGLN1 (0.50) ALDH1A1LMNAHSD17B10TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170145223-A1 Fireproof Composition and Use Thereof HILTI AKTIENGESELLSCHAFT (LI) 2017-05-25 US disclosed
US-8716368-B2 Unsaturated polyester resin or vinyl ester resin composition DSM IP ASSETS B.V. (NL) 2014-05-06 US disclosed
EP-1888680-B1 UNSATURATED POLYESTER RESIN OR VINYL ESTER RESIN COMPOSITION DSM IP ASSETS BV (NL) 2011-10-05 EP disclosed
US-20090156750-A1 Unsaturated polyester resin or vinyl ester resin composition DSM IP ASSETS B.V. (NL) 2009-06-18 US disclosed
EP-1888680-A1 UNSATURATED POLYESTER RESIN OR VINYL ESTER RESIN COMPOSITION DSMIP Assets B.V. (NL) 2008-02-20 EP disclosed
WO-2006131295-A1 UNSATURATED POLYESTER RESIN OR VINYL ESTER RESIN COMPOSITION DSM IP ASSETS B.V. (NL) 2006-12-14 WO disclosed