Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670804 | 1.00 | NAMPT (0.39) | NAMPTQDPRMCHR1HTR1DMEN1 | |
| SCHEMBL24670803 | 0.94 | NAMPT (0.38) | NAMPTQDPRMCHR1HTR1DMEN1 | |
| SCHEMBL29803599 | 0.93 | NAMPT (0.41) | NAMPTMAPTKMT2APRMT5WDR77 | |
| SCHEMBL24669444 | 0.93 | NAMPT (0.42) | NAMPTQDPRMCHR1HTR1DSLC6A4 | |
| SCHEMBL24669435 | 0.93 | NAMPT (0.42) | NAMPTQDPRMCHR1HTR1DSLC6A4 | |
| SCHEMBL24671257 | 0.92 | NAMPT (0.39) | NAMPTQDPRABCB1PRMT5WDR77 | |
| SCHEMBL24670897 | 0.92 | NAMPT (0.39) | NAMPTQDPRABCB1PRMT5WDR77 | |
| SCHEMBL24671356 | 0.91 | NAMPT (0.40) | NAMPTMAPTKMT2ALMNANPSR1 | |
| SCHEMBL24671289 | 0.91 | NAMPT (0.40) | NAMPTMAPTKMT2ALMNANPSR1 | |
| SCHEMBL29803446 | 0.91 | NAMPT (0.40) | NAMPTMAPTKMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |