SCHEMBL24670841

SCHEMBL24670841

Cc1c(NC(=O)c2ccc(C3=CCNCC3)c(F)c2)ccc(C2=CCNCC2)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 4/20 0.47
CDK9 P50750 4/20 0.47
BTK Q06187 1/20 0.45
WDR5 P61964 2/20 0.38
BRPF1 P55201 1/20 0.38
HTR6 P50406 2/20 0.36
NPC1 O15118 1/20 0.35
CASP3 P42574 1/20 0.35
RAB9A P51151 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
BRAF P15056 1/20 0.35
MAPT P10636 1/20 0.35
KCNQ3 O43525 1/20 0.35
KCNQ2 O43526 1/20 0.35
KCNE1 P15382 1/20 0.35
KCNQ1 P51787 1/20 0.35
KCNQ5 Q9NR82 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TAS1R2 Q8TE23 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29803295 1.00 CCNT1 (0.47) CCNT1CDK9BTKWDR5BRPF1
SCHEMBL29803874 0.90 CCNT1 (0.48) CCNT1CDK9BTKWDR5BRPF1
SCHEMBL29803760 0.90 CCNT1 (0.46) CCNT1CDK9BTKWDR5BRPF1
SCHEMBL24671364 0.90 CCNT1 (0.48) CCNT1CDK9BTKWDR5BRPF1
SCHEMBL29803370 0.84 CCNT1 (0.49) CCNT1CDK9BTKWDR5BRPF1
SCHEMBL29803563 0.84 CCNT1 (0.48) CCNT1CDK9BTKWDR5BRPF1
SCHEMBL24669304 0.84 CCNT1 (0.47) CCNT1CDK9BTKWDR5BRPF1
SCHEMBL29803753 0.84 CCNT1 (0.45) CCNT1CDK9BTKNPC1RAB9A
SCHEMBL29803667 0.84 CCNT1 (0.47) CCNT1CDK9BTKWDR5BRPF1
SCHEMBL24670269 0.83 CCNT1 (0.49) CCNT1CDK9BTKWDR5BRPF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022192162-A1 NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2022-09-15 WO disclosed