Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.48 |
| ▸ | CDK9 | P50750 | 4/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803874 | 1.00 | CCNT1 (0.48) | CCNT1CDK9BTKWDR5BRPF1 | |
| SCHEMBL29803563 | 0.90 | CCNT1 (0.48) | CCNT1CDK9BTKWDR5BRPF1 | |
| SCHEMBL29803295 | 0.90 | CCNT1 (0.47) | CCNT1CDK9BTKWDR5BRPF1 | |
| SCHEMBL24670841 | 0.90 | CCNT1 (0.47) | CCNT1CDK9BTKWDR5BRPF1 | |
| SCHEMBL29803370 | 0.86 | CCNT1 (0.49) | CCNT1CDK9BTKWDR5BRPF1 | |
| SCHEMBL24669304 | 0.85 | CCNT1 (0.47) | CCNT1CDK9BTKWDR5BRPF1 | |
| SCHEMBL29803667 | 0.85 | CCNT1 (0.47) | CCNT1CDK9BTKWDR5BRPF1 | |
| SCHEMBL29803760 | 0.85 | CCNT1 (0.46) | CCNT1CDK9BTKWDR5BRPF1 | |
| SCHEMBL24670269 | 0.84 | CCNT1 (0.49) | CCNT1CDK9BTKWDR5BRPF1 | |
| SCHEMBL29803449 | 0.84 | CCNT1 (0.49) | CCNT1CDK9BTKWDR5BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |