Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669483 | 1.00 | NAMPT (0.42) | NAMPTCD274MCHR1MAPTALDH1A1 | |
| SCHEMBL24670225 | 0.89 | NAMPT (0.43) | NAMPTCD274 | |
| SCHEMBL29803349 | 0.89 | NAMPT (0.43) | NAMPTCD274 | |
| SCHEMBL24671335 | 0.88 | MAPT (0.37) | NAMPTMAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL29803846 | 0.88 | MAPT (0.37) | NAMPTMAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL30182331 | 0.88 | NAMPT (0.44) | NAMPTCD274MAPTSMN1; SMN2 | |
| SCHEMBL24669386 | 0.88 | NAMPT (0.44) | NAMPTCD274MAPTSMN1; SMN2 | |
| SCHEMBL24669388 | 0.88 | NAMPT (0.44) | NAMPTCD274MAPTSMN1; SMN2 | |
| SCHEMBL24892227 | 0.84 | NAMPT (0.41) | NAMPTCD274 | |
| SCHEMBL30182523 | 0.84 | NAMPT (0.41) | NAMPTCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |