Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803846 | 1.00 | MAPT (0.37) | MAPTNAMPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL29803497 | 0.90 | NAMPT (0.37) | MAPTNAMPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL24670917 | 0.88 | NAMPT (0.42) | MAPTNAMPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL24671548 | 0.88 | NAMPT (0.39) | MAPTNAMPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL24669483 | 0.88 | NAMPT (0.42) | MAPTNAMPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL29803457 | 0.88 | NAMPT (0.47) | NAMPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL24669283 | 0.84 | NAMPT (0.45) | MAPTNAMPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL29803544 | 0.80 | NAMPT (0.36) | MAPTNAMPTPDE10AKIT | |
| SCHEMBL29803333 | 0.80 | TRPV1 (0.37) | MAPTNAMPTLMNASMN1; SMN2 | |
| SCHEMBL29803749 | 0.80 | IMPDH2 (0.37) | NAMPTKDM4ELMNASMN1; SMN2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |