Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3565907 | 0.86 | USP2 (0.51) | USP2SMN1; SMN2HTTATMALDH1A1 | |
| SCHEMBL27365987 | 0.85 | USP2 (0.50) | USP2SMN1; SMN2HTTATMALDH1A1 | |
| SCHEMBL25524991 | 0.84 | USP2 (0.46) | USP2SMN1; SMN2HTTATMALDH1A1 | |
| SCHEMBL2737190 | 0.82 | HRH3 (0.58) | USP2SMN1; SMN2HTTATMALDH1A1 | |
| SCHEMBL29162701 | 0.82 | USP2 (0.47) | USP2SMN1; SMN2HTTATMALDH1A1 | |
| SCHEMBL20847001 | 0.82 | USP2 (0.47) | USP2SMN1; SMN2HTTATMALDH1A1 | |
| SCHEMBL5599546 | 0.81 | USP2 (0.53) | USP2SMN1; SMN2HTTATMALDH1A1 | |
| SCHEMBL19297036 | 0.81 | USP2 (0.46) | USP2SMN1; SMN2HTTATMALDH1A1 | |
| SCHEMBL22994977 | 0.81 | USP2 (0.46) | USP2SMN1; SMN2HTTATMALDH1A1 | |
| SCHEMBL25524072 | 0.80 | USP2 (0.43) | USP2SMN1; SMN2HTTATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |