SCHEMBL25524072

SCHEMBL25524072

CCC(CN)C(C)N1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HTT P42858 2/20 0.40
ATM Q13315 1/20 0.40
MAPK1 P28482 2/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
DPP4 P27487 1/20 0.39
HRH3 Q9Y5N1 1/20 0.38
HPGD P15428 1/20 0.38
EPHX2 P34913 1/20 0.37
DTYMK P23919 1/20 0.37
GPR119 Q8TDV5 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25524789 0.85 GPR119 (0.37) USP2SMN1; SMN2HTTATMMAPK1
SCHEMBL25524991 0.84 USP2 (0.46) USP2SMN1; SMN2HTTATMMAPK1
SCHEMBL22994977 0.84 USP2 (0.46) USP2SMN1; SMN2HTTATMMAPK1
SCHEMBL25525673 0.83 GPR119 (0.37) USP2SMN1; SMN2HTTATMMAPK1
SCHEMBL29162701 0.82 USP2 (0.47) USP2SMN1; SMN2HTTATMMAPK1
SCHEMBL20847001 0.82 USP2 (0.47) USP2SMN1; SMN2HTTATMMAPK1
SCHEMBL4379500 0.82 USP2 (0.50) USP2SMN1; SMN2HTTATMALDH1A1
SCHEMBL25684889 0.81 GPR119 (0.37) USP2SMN1; SMN2HTTATMMAPK1
SCHEMBL24670979 0.80 USP2 (0.49) USP2SMN1; SMN2HTTATMMAPK1
SCHEMBL4391742 0.80 USP2 (0.49) USP2SMN1; SMN2HTTATMMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023078946-A1 LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY ZIPHIUS VACCINES NV (BE) 2023-05-11 WO disclosed
WO-2023078954-A1 LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY ZIPHIUS VACCINES NV (BE) 2023-05-11 WO disclosed