Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.36 |
| ▸ | GRM5 | P41594 | 6/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | LIPC | P11150 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669283 | 0.88 | NAMPT (0.45) | NAMPTACKR3PDK4KITWNT3A | |
| SCHEMBL24670346 | 0.86 | NAMPT (0.48) | NAMPTACKR3PDK4KITWNT3A | |
| SCHEMBL29803497 | 0.84 | NAMPT (0.37) | NAMPTACKR3 | |
| SCHEMBL24669280 | 0.83 | NAMPT (0.62) | NAMPTACKR3PDK4KITWNT3A | |
| SCHEMBL24670539 | 0.80 | NAMPT (0.32) | NAMPTACKR3 | |
| SCHEMBL29803264 | 0.80 | RXFP1 (0.34) | — | |
| SCHEMBL24671539 | 0.80 | NAMPT (0.44) | NAMPTACKR3PDK4KITWNT3A | |
| SCHEMBL24669980 | 0.79 | RXFP1 (0.34) | NAMPT | |
| SCHEMBL5223668 | 0.78 | NAMPT (0.49) | NAMPTACKR3PDK4GRM1GRM5 | |
| SCHEMBL24671091 | 0.76 | NAMPT (0.47) | NAMPTPDK4KITGRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |