Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ESRRG | P62508 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803846 | 0.90 | MAPT (0.37) | NAMPTTP53ACKR3KDM4ELMNA | |
| SCHEMBL24671335 | 0.90 | MAPT (0.37) | NAMPTTP53ACKR3KDM4ELMNA | |
| SCHEMBL24671548 | 0.88 | NAMPT (0.39) | NAMPTTP53ACKR3RXFP1KDM4E | |
| SCHEMBL24670539 | 0.88 | NAMPT (0.32) | NAMPTACKR3 | |
| SCHEMBL29803457 | 0.88 | NAMPT (0.47) | NAMPTRXFP1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL24671055 | 0.84 | NAMPT (0.45) | NAMPTACKR3 | |
| SCHEMBL29803544 | 0.80 | NAMPT (0.36) | NAMPTESRRGMAPT | |
| SCHEMBL29803333 | 0.80 | TRPV1 (0.37) | NAMPTLMNASMN1; SMN2MAPT | |
| SCHEMBL29803749 | 0.80 | IMPDH2 (0.37) | NAMPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL24670448 | 0.79 | NAMPT (0.40) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |