SCHEMBL24671122

SCHEMBL24671122

Cc1cc(N)ccc1NCCN

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
RAD52 P43351 1/20 0.41
HTT P42858 1/20 0.41
PDE10A Q9Y233 1/20 0.41
NQO2 P16083 3/20 0.40
IDO1 P14902 2/20 0.40
CASP1 P29466 1/20 0.39
AR P10275 1/20 0.38
VDR P11473 1/20 0.38
CA12 O43570 1/20 0.38
CA3 P07451 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5461317 0.98 ALDH1A1 (0.43) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL7136159 0.89 KAT2B (0.48) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL6369704 0.86 NQO2 (0.47) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL11935076 0.86 NQO2 (0.49) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL6369919 0.85 NQO2 (0.54) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL6377800 0.85 NQO2 (0.54) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL5467473 0.85 MAPT (0.45) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL15196187 0.85 ALDH1A1 (0.45) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL4955142 0.85 NQO2 (0.46) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL4953305 0.83 NQO2 (0.53) ALDH1A1MAPTCYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022192162-A1 NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2022-09-15 WO disclosed