Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803211 | 1.00 | TMPRSS2 (0.51) | TMPRSS2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL24670238 | 0.92 | TMPRSS2 (0.46) | TMPRSS2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL29803214 | 0.91 | TMPRSS2 (0.52) | TMPRSS2NPC1RAB9ANAMPTPLAU | |
| SCHEMBL24669442 | 0.91 | TMPRSS2 (0.46) | TMPRSS2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL24671330 | 0.91 | TMPRSS2 (0.46) | TMPRSS2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL24670819 | 0.90 | TMPRSS2 (0.44) | TMPRSS2 | |
| SCHEMBL24670178 | 0.90 | TMPRSS2 (0.52) | TMPRSS2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL24669441 | 0.90 | TMPRSS2 (0.53) | TMPRSS2NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL29802916 | 0.89 | TMPRSS2 (0.43) | TMPRSS2NPC1KMT2ARAB9ANAMPT | |
| SCHEMBL24670865 | 0.89 | TMPRSS2 (0.52) | TMPRSS2NPC1KMT2ARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |