Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 7/20 | 0.53 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | QDPR | P09417 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670801 | 0.91 | TMPRSS2 (0.45) | TMPRSS2HTR1DSLC6A4PLAUPLAT | |
| SCHEMBL24670178 | 0.90 | TMPRSS2 (0.52) | TMPRSS2HTR1DSLC6A4PLAUPLAT | |
| SCHEMBL29803211 | 0.90 | TMPRSS2 (0.51) | TMPRSS2HTR1DSLC6A4PLAUPLAT | |
| SCHEMBL24670865 | 0.90 | TMPRSS2 (0.52) | TMPRSS2PLAUPLATNPC1RAB9A | |
| SCHEMBL24671177 | 0.90 | TMPRSS2 (0.51) | TMPRSS2HTR1DSLC6A4PLAUPLAT | |
| SCHEMBL29803378 | 0.89 | TMPRSS2 (0.52) | TMPRSS2HTR1DSLC6A4NPC1RAB9A | |
| SCHEMBL24670214 | 0.89 | TMPRSS2 (0.52) | TMPRSS2HTR1DSLC6A4NPC1RAB9A | |
| SCHEMBL24671261 | 0.88 | QDPR (0.43) | TMPRSS2HTR1DSLC6A4PLAUPLAT | |
| SCHEMBL24671463 | 0.88 | TMPRSS2 (0.49) | TMPRSS2HTR1DSLC6A4NPC1RAB9A | |
| SCHEMBL24891766 | 0.88 | TMPRSS2 (0.47) | TMPRSS2HTR1DSLC6A4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |