Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | NPY2R | P49146 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802918 | 1.00 | MAPT (0.50) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL29802966 | 0.89 | MAPT (0.55) | MAPTALDH1A1KMT2AKDM4EMCL1 | |
| SCHEMBL29803013 | 0.85 | NPC1 (0.58) | MAPTALDH1A1KMT2AKDM4EMCL1 | |
| SCHEMBL24891925 | 0.84 | NPC1 (0.60) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL30180770 | 0.84 | NPC1 (0.60) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL29803543 | 0.83 | MAPT (0.55) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL24669340 | 0.83 | MAPT (0.55) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL29802893 | 0.83 | MAPT (0.46) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL29803630 | 0.82 | ALDH1A1 (0.54) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL29802994 | 0.82 | CHRM1 (0.44) | MAPTKMT2ARAB9AAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |