Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 3/20 | 0.36 |
| ▸ | GRM5 | P41594 | 5/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670577 | 0.91 | PDK4 (0.39) | PDK4CDK9GRM5GRM1NAMPT | |
| SCHEMBL24671139 | 0.90 | NR1H2 (0.40) | NR1H2PDK4CDK9GRM5GRM1 | |
| SCHEMBL24670136 | 0.90 | NR1H2 (0.40) | NR1H2PDK4CDK9GRM5GRM1 | |
| SCHEMBL24670675 | 0.89 | NR1H2 (0.38) | NR1H2PDK4CDK9GRM5GRM1 | |
| SCHEMBL24670618 | 0.89 | NR1H2 (0.39) | NR1H2PDK4CDK9GRM5GRM1 | |
| SCHEMBL24669395 | 0.88 | NR1H2 (0.39) | NR1H2PDK4CDK9GRM5GRM1 | |
| SCHEMBL24670250 | 0.88 | GRM1 (0.36) | NR1H2PDK4CDK9GRM5GRM1 | |
| SCHEMBL24671099 | 0.88 | PDK4 (0.38) | PDK4CDK9GRM5GRM1NAMPT | |
| SCHEMBL24669650 | 0.86 | PDK4 (0.35) | PDK4CDK9GRM5GRM1NAMPT | |
| SCHEMBL24670260 | 0.86 | NR1H2 (0.37) | NR1H2PDK4CDK9GRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |