Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 13/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803727 | 1.00 | NAMPT (0.61) | NAMPTPIK3CAMTORWNT3AESR2 | |
| SCHEMBL29803570 | 0.96 | NAMPT (0.58) | NAMPTPIK3CAMTORWNT3AESR2 | |
| SCHEMBL29803581 | 0.96 | NAMPT (0.61) | NAMPTPIK3CAMTORWNT3AESR2 | |
| SCHEMBL24671434 | 0.96 | NAMPT (0.61) | NAMPTPIK3CAMTORWNT3AESR2 | |
| SCHEMBL29803636 | 0.90 | NAMPT (0.67) | NAMPTPIK3CAMTORESR2NR1H2 | |
| SCHEMBL24670854 | 0.90 | NAMPT (0.67) | NAMPTPIK3CAMTORESR2NR1H2 | |
| SCHEMBL24892302 | 0.89 | NAMPT (0.68) | NAMPTPIK3CAMTORTMPRSS2 | |
| SCHEMBL30182726 | 0.89 | NAMPT (0.68) | NAMPTPIK3CAMTORTMPRSS2 | |
| SCHEMBL29803738 | 0.88 | NAMPT (0.54) | NAMPTWNT3ACDK7CDK13CDK12 | |
| SCHEMBL24892052 | 0.86 | NAMPT (0.61) | NAMPTWNT3ACDK7CDK13CDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |