Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.37 |
| ▸ | PLG | P00747 | 3/20 | 0.37 |
| ▸ | PLAU | P00749 | 3/20 | 0.37 |
| ▸ | PLAT | P00750 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802955 | 0.95 | TMPRSS2 (0.45) | TMPRSS2ITGB3ITGA2BNAMPTMAPT | |
| SCHEMBL24671223 | 0.95 | TMPRSS2 (0.45) | TMPRSS2ITGB3ITGA2BNAMPTMAPT | |
| SCHEMBL29803078 | 0.91 | TMPRSS2 (0.42) | TMPRSS2ITGB3ITGA2BNAMPTKLKB1 | |
| SCHEMBL24668998 | 0.91 | TMPRSS2 (0.42) | TMPRSS2ITGB3ITGA2BNAMPTKLKB1 | |
| SCHEMBL24669447 | 0.88 | TMPRSS2 (0.48) | TMPRSS2NAMPTKLKB1MAPTLMNA | |
| SCHEMBL29803214 | 0.88 | TMPRSS2 (0.52) | TMPRSS2ITGB3ITGA2BNAMPTKLKB1 | |
| SCHEMBL30181071 | 0.87 | MAPT (0.37) | TMPRSS2NAMPTMAPTTP53LMNA | |
| SCHEMBL30181059 | 0.87 | TMPRSS2 (0.48) | TMPRSS2ITGB3ITGA2BNAMPTPLAU | |
| SCHEMBL24669387 | 0.86 | TMPRSS2 (0.45) | TMPRSS2NAMPTF2MAPT | |
| SCHEMBL24891885 | 0.86 | TMPRSS2 (0.45) | TMPRSS2NAMPTF2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |