Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 7/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802955 | 1.00 | TMPRSS2 (0.45) | TMPRSS2ITGB3ITGA2BMAPTTRPV1 | |
| SCHEMBL24671334 | 0.95 | TMPRSS2 (0.43) | TMPRSS2ITGB3ITGA2BMAPTNAMPT | |
| SCHEMBL29802915 | 0.89 | TMPRSS2 (0.49) | TMPRSS2ITGB3ITGA2BMAPTNAMPT | |
| SCHEMBL30181059 | 0.89 | TMPRSS2 (0.48) | TMPRSS2ITGB3ITGA2BMAPTNAMPT | |
| SCHEMBL30181071 | 0.89 | MAPT (0.37) | TMPRSS2MAPTTRPV1NAMPTBTK | |
| SCHEMBL29803214 | 0.88 | TMPRSS2 (0.52) | TMPRSS2ITGB3ITGA2BMAPTTRPV1 | |
| SCHEMBL24891766 | 0.87 | TMPRSS2 (0.47) | TMPRSS2MAPTNAMPTHDAC1TP53 | |
| SCHEMBL24668998 | 0.86 | TMPRSS2 (0.42) | TMPRSS2ITGB3ITGA2BNAMPTJAK2 | |
| SCHEMBL29803078 | 0.86 | TMPRSS2 (0.42) | TMPRSS2ITGB3ITGA2BNAMPTJAK2 | |
| SCHEMBL24669387 | 0.86 | TMPRSS2 (0.45) | TMPRSS2MAPTNAMPTBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |