SCHEMBL2467143

SCHEMBL2467143

C=CC(=O)OC(C)C(=O)O.C=CC(=O)OC(C)C(=O)O.C=CC(=O)OC(C)C(=O)O.CCC(CO)(CO)CO

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HIF1A Q16665 1/20 0.43
THRB P10828 1/20 0.41
TSHR P16473 4/20 0.37
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2459439 0.92 ALDH1A1 (0.47) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL9722088 0.83 ALDH1A1 (0.46) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Ethylene Glycol SCHEMBL2459292 0.83 TSHR (0.44) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL2184214 0.82 TSHR (0.45) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL37396 0.82 TSHR (0.45) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL183980 0.80 TSHR (0.43) ALDH1A1TP53CYP3A4HIF1ATSHR
SCHEMBL1919847 0.80 TSHR (0.43) ALDH1A1TP53CYP3A4HIF1ATSHR
SCHEMBL1919371 0.80 TSHR (0.43) ALDH1A1TP53CYP3A4HIF1ATSHR
SCHEMBL10953217 0.80 TSHR (0.43) ALDH1A1TP53CYP3A4HIF1ATSHR
SCHEMBL184163 0.80 TSHR (0.43) ALDH1A1TP53CYP3A4HIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3474952-B1 COMPOSITIONS CONTAINING LATEX PARTICLES AND UV ABSORBERS ROHM & HAAS (US) 2021-07-28 EP claimed
US-20190133913-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND UV ABSORBERS ROHM & HAAS (US) 2019-05-09 US claimed
EP-3474952-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND UV ABSORBERS Rohm and Haas Company (US) 2019-05-01 EP claimed
WO-2017222570-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND UV ABSORBERS ROHM AND HAAS COMPANY (US) 2017-12-28 WO claimed
EP-0376590-B1 Monomer or polymer composition derived from acryloxy alkyl cyanoacetamides ROHM & HAAS (US) 1994-11-30 EP claimed
US-5021511-A Reacted with carbon-michael addition acceptor; coatings, adhesives, caulks, mastics; nonhydrolyzing ROHM AND HAAS COMPANY (US) 1991-06-04 US claimed
EP-0376590-A2 Monomer or polymer composition derived from acryloxy alkyl cyanoacetamides ROHM AND HAAS COMPANY (US) 1990-07-04 EP claimed
US-4877818-A PHOTORESISTS ROHM AND HAAS COMPANY (US) 1989-10-31 US claimed
EP-0176356-B1 PHOTOSENSITIVE POLYMER COMPOSITIONS, ELECTROPHORETIC DEPOSITION PROCESSES USING SAME, AND THE USE OF SAME IN FORMING FILMS ON SUBSTRATES ROHM AND HAAS COMPANY (US) 1988-11-02 EP claimed
EP-0176356-A2 Photosensitive polymer compositions, electrophoretic deposition processes using same, and the use of same in forming films on substrates ROHM AND HAAS COMPANY (US) 1986-04-02 EP claimed
US-20190133913-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND UV ABSORBERS ROHM & HAAS (US) 2019-05-09 US disclosed
EP-3474952-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND UV ABSORBERS Rohm and Haas Company (US) 2019-05-01 EP disclosed
WO-2017222570-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND UV ABSORBERS ROHM AND HAAS COMPANY (US) 2017-12-28 WO disclosed
EP-1632281-B1 Process for absorbing hydrophobic substances in polymers having an hollow structure ROHM & HAAS (US) 2011-09-14 EP disclosed
EP-1510318-B1 Process for manufacturing polymers ROHM & HAAS (US) 2009-07-01 EP disclosed
EP-1092421-A2 Method for preparing ultraviolet radiation absorbing compositions ROHM AND HAAS COMPANY (US) 2001-04-18 EP disclosed
EP-0376590-B1 Monomer or polymer composition derived from acryloxy alkyl cyanoacetamides ROHM & HAAS (US) 1994-11-30 EP disclosed
US-5021511-A Reacted with carbon-michael addition acceptor; coatings, adhesives, caulks, mastics; nonhydrolyzing ROHM AND HAAS COMPANY (US) 1991-06-04 US disclosed
EP-0376590-A2 Monomer or polymer composition derived from acryloxy alkyl cyanoacetamides ROHM AND HAAS COMPANY (US) 1990-07-04 EP disclosed
US-4877818-A PHOTORESISTS ROHM AND HAAS COMPANY (US) 1989-10-31 US disclosed