Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2741634 | 0.87 | OGA (0.43) | OGAHRH3ASIC3ACACBKDM4E | |
| SCHEMBL24671706 | 0.82 | MAOA (0.52) | — | |
| SCHEMBL24817824 | 0.81 | OGA (0.41) | OGAHRH3ACACBKDM4EALDH1A1 | |
| SCHEMBL12184930 | 0.80 | HRH3 (0.42) | OGAHRH3ASIC3KDM4EALDH1A1 | |
| SCHEMBL10199349 | 0.80 | HRH3 (0.48) | OGAHRH3ASIC3KDM4EALDH1A1 | |
| SCHEMBL13499613 | 0.78 | HRH3 (0.43) | OGAHRH3ASIC3KDM4EALDH1A1 | |
| SCHEMBL24616867 | 0.77 | HSD17B3 (0.42) | OGAHRH3ASIC3KDM4EALDH1A1 | |
| SCHEMBL21361596 | 0.77 | CARM1 (0.48) | HRH3ASIC3ACACB | |
| SCHEMBL21361477 | 0.77 | HTR2A (0.44) | HRH3ASIC3ACACBKCNH2 | |
| SCHEMBL15142196 | 0.77 | DRD1 (0.54) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235715-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |