Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 5/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29803355 | 0.94 | TRPV1 (0.40) | TMPRSS2EGLN1TRPV1 | |
| SCHEMBL24892250 | 0.88 | PRKAA2 (0.40) | TMPRSS2EGLN1NAMPTALDH1A1NPC1 | |
| SCHEMBL24891807 | 0.88 | PRKAA2 (0.40) | TMPRSS2EGLN1NAMPTALDH1A1NPC1 | |
| SCHEMBL24669387 | 0.87 | TMPRSS2 (0.45) | TMPRSS2F2NAMPTALDH1A1MAPT | |
| SCHEMBL24891885 | 0.87 | TMPRSS2 (0.45) | TMPRSS2F2NAMPTALDH1A1MAPT | |
| SCHEMBL24669641 | 0.86 | EGLN1 (0.41) | F2JAK2JAK1EGLN1NAMPT | |
| SCHEMBL24891672 | 0.85 | NAMPT (0.43) | TMPRSS2EGLN1NAMPTALDH1A1 | |
| SCHEMBL30181035 | 0.85 | NAMPT (0.43) | TMPRSS2EGLN1NAMPTALDH1A1 | |
| SCHEMBL30180909 | 0.85 | TMPRSS2 (0.39) | TMPRSS2F2JAK2JAK1EGLN1 | |
| SCHEMBL29802997 | 0.84 | PTPN11 (0.39) | TMPRSS2F2JAK2JAK1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |