Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 13/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891672 | 1.00 | NAMPT (0.43) | NAMPTEGLN1TMPRSS2ALDH1A1BTK | |
| SCHEMBL24891675 | 0.92 | NAMPT (0.44) | NAMPTEGLN1TMPRSS2ALDH1A1 | |
| SCHEMBL24891885 | 0.91 | TMPRSS2 (0.45) | NAMPTTMPRSS2ALDH1A1BTK | |
| SCHEMBL24669387 | 0.91 | TMPRSS2 (0.45) | NAMPTTMPRSS2ALDH1A1BTK | |
| SCHEMBL30180909 | 0.88 | TMPRSS2 (0.39) | NAMPTEGLN1TMPRSS2ALDH1A1BTK | |
| SCHEMBL24892250 | 0.88 | PRKAA2 (0.40) | NAMPTEGLN1TMPRSS2ALDH1A1 | |
| SCHEMBL24891807 | 0.88 | PRKAA2 (0.40) | NAMPTEGLN1TMPRSS2ALDH1A1 | |
| SCHEMBL24669641 | 0.86 | EGLN1 (0.41) | NAMPTEGLN1ALDH1A1 | |
| SCHEMBL30180918 | 0.85 | TMPRSS2 (0.40) | NAMPTTMPRSS2BTK | |
| SCHEMBL24671535 | 0.85 | TMPRSS2 (0.39) | NAMPTEGLN1TMPRSS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | claimed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |