Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.57 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669380 | 0.86 | GRM4 (0.56) | MAPTMEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL29803730 | 0.86 | GRM4 (0.56) | MAPTMEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL2683383 | 0.84 | MAPT (0.52) | MAPTMEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL29803408 | 0.82 | MAOB (0.70) | MAPTMEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL24669338 | 0.82 | MAOB (0.70) | MAPTMEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL24670229 | 0.82 | MAOB (0.56) | MAPTMEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL24670881 | 0.81 | MAOB (0.53) | MAPTMEN1KMT2ASMN1; SMN2MAOB | |
| SCHEMBL24670265 | 0.80 | GRM4 (0.55) | MAPTMEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL24670851 | 0.79 | MAOB (0.59) | MAPTMEN1KMT2AKCNQ3KCNQ2 | |
| SCHEMBL29803287 | 0.79 | MAOB (0.59) | MAPTMEN1KMT2AKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |