Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669338 | 0.87 | MAOB (0.70) | MAOBMAPTPTGDR2RAB9ANPC1 | |
| SCHEMBL29803408 | 0.87 | MAOB (0.70) | MAOBMAPTPTGDR2RAB9ANPC1 | |
| SCHEMBL24670851 | 0.83 | MAOB (0.59) | MAOBMAPTRAB9ANPC1MEN1 | |
| SCHEMBL29803287 | 0.83 | MAOB (0.59) | MAOBMAPTRAB9ANPC1MEN1 | |
| SCHEMBL24671323 | 0.82 | MAOB (0.65) | MAOBMAPTRAB9ANPC1NPSR1 | |
| SCHEMBL24671538 | 0.82 | MAPT (0.58) | MAOBMAPTRAB9ANPC1MEN1 | |
| SCHEMBL24670922 | 0.81 | TP53 (0.63) | MAOBMAPTRAB9ANPC1MEN1 | |
| SCHEMBL24670043 | 0.80 | MAPT (0.77) | MAOBMAPTRAB9ANPC1MEN1 | |
| SCHEMBL29803768 | 0.80 | MAPT (0.77) | MAOBMAPTRAB9ANPC1MEN1 | |
| SCHEMBL24670735 | 0.80 | MAOB (0.62) | MAOBMAPTPTGDR2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |