Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670895 | 0.91 | TMPRSS2 (0.44) | NAMPTTMPRSS2ST14MEN1KMT2A | |
| SCHEMBL24891798 | 0.90 | TMPRSS2 (0.44) | NAMPTTMPRSS2MEN1KMT2AKDM4E | |
| SCHEMBL24891800 | 0.84 | TMPRSS2 (0.46) | NAMPTTMPRSS2MEN1KMT2AKDM4E | |
| SCHEMBL24892365 | 0.81 | ST14 (0.55) | ST14MEN1KMT2AMAPTKDM4E | |
| SCHEMBL24670896 | 0.81 | TMPRSS2 (0.46) | NAMPTTMPRSS2MEN1KMT2AMAPT | |
| SCHEMBL24669387 | 0.81 | TMPRSS2 (0.45) | NAMPTTMPRSS2MEN1KMT2AMAPT | |
| SCHEMBL24891885 | 0.81 | TMPRSS2 (0.45) | NAMPTTMPRSS2MEN1KMT2AMAPT | |
| SCHEMBL29802880 | 0.80 | TMPRSS2 (0.48) | TMPRSS2ST14MEN1KMT2AMAPT | |
| SCHEMBL29803078 | 0.80 | TMPRSS2 (0.42) | NAMPTTMPRSS2ST14MEN1KMT2A | |
| SCHEMBL24891809 | 0.79 | NPC1 (0.40) | NAMPTMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |