Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 7/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891885 | 0.91 | TMPRSS2 (0.45) | TMPRSS2F2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL24669387 | 0.91 | TMPRSS2 (0.45) | TMPRSS2F2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL24671556 | 0.90 | NAMPT (0.42) | TMPRSS2SMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL24891800 | 0.90 | TMPRSS2 (0.46) | TMPRSS2F2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL30181035 | 0.83 | NAMPT (0.43) | TMPRSS2NAMPT | |
| SCHEMBL24891666 | 0.83 | NAMPT (0.43) | TMPRSS2KDM4ENAMPTNOD1 | |
| SCHEMBL24891807 | 0.82 | PRKAA2 (0.40) | TMPRSS2KDM4ENPC1RAB9ANAMPT | |
| SCHEMBL24892250 | 0.82 | PRKAA2 (0.40) | TMPRSS2KDM4ENPC1RAB9ANAMPT | |
| SCHEMBL30181321 | 0.81 | TMPRSS2 (0.46) | TMPRSS2F2NPC1RAB9ANAMPT | |
| SCHEMBL24670895 | 0.81 | TMPRSS2 (0.44) | TMPRSS2SMN1; SMN2MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | claimed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |