Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 8/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 8/20 | 0.44 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15205667 | 0.84 | MTOR (0.48) | MAOBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24669456 | 0.83 | NPC1 (0.68) | MAOBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL29803410 | 0.83 | NPC1 (0.68) | MAOBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL15205141 | 0.82 | KDM4E (0.60) | NPC1RAB9AMEN1KMT2AKCNQ3 | |
| SCHEMBL15205296 | 0.81 | RAB9A (0.64) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL24670293 | 0.81 | KCNQ3 (0.60) | MAOBKCNQ3KCNQ2KCNQ5KCNE1 | |
| SCHEMBL24671390 | 0.79 | MAOB (0.45) | MAOBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24671014 | 0.78 | KCNQ3 (0.49) | MAOBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25983228 | 0.78 | RAB9A (0.65) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL15205496 | 0.78 | SNCA (0.46) | NPC1RAB9AKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |