SCHEMBL24671736

SCHEMBL24671736

CC1CCC[C@H]1CNC(=O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BCHE P06276 3/20 0.50
CNR1 P21554 3/20 0.47
CNR2 P34972 2/20 0.47
RAB9A P51151 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24671773 1.00 BCHE (0.50) BCHECNR1CNR2RAB9AMEN1
SCHEMBL2364197 0.77 BCHE (0.62) BCHECNR1CNR2RAB9AMEN1
SCHEMBL17294613 0.71 BCHE (0.44) BCHECNR1CNR2RAB9AMEN1
SCHEMBL17294719 0.71 BCHE (0.44) BCHECNR1CNR2RAB9AMEN1
SCHEMBL22917068 0.70 CNR1 (0.48) CNR1CNR2RAB9ASLC6A2SLC6A3
SCHEMBL6432512 0.70 MEN1 (0.68) CNR1CNR2MEN1KMT2A
SCHEMBL12929309 0.69 CNR1 (0.46) BCHECNR1CNR2MEN1KMT2A
SCHEMBL12899991 0.69 CNR1 (0.46) BCHECNR1CNR2MEN1KMT2A
SCHEMBL17294704 0.68 CCR2 (0.54) KMT2ASLC6A2SLC6A3
SCHEMBL6432979 0.67 CNR1 (0.69) CNR1CNR2RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3148518-B1 NOVEL COMPOUNDS AS ANTI-TUBERCULAR AGENTS SPHAERA PHARMA PRIVATE LTD (IN) 2022-11-30 EP disclosed