Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17294687 | 0.83 | CHRM2 (0.55) | CHRM2CHRM1CHRM3 | |
| SCHEMBL17294689 | 0.83 | CHRM2 (0.55) | CHRM2CHRM1CHRM3 | |
| SCHEMBL17294683 | 0.76 | CCR1 (0.58) | CCR1SSTR1SSTR4CHRM2CHRM1 | |
| SCHEMBL17294626 | 0.76 | CCR1 (0.58) | CCR1SSTR1SSTR4CHRM2CHRM1 | |
| SCHEMBL17294692 | 0.76 | CCR1 (0.58) | CCR1SSTR1SSTR4CHRM2CHRM1 | |
| SCHEMBL17294645 | 0.75 | CHRM2 (0.56) | CCR1LMNASSTR1SSTR4CHRM2 | |
| SCHEMBL24671896 | 0.73 | CCR1 (0.55) | CCR1 | |
| SCHEMBL25464076 | 0.71 | MAPT (0.46) | CCR1LMNACHRM2CHRM1CHRM3 | |
| SCHEMBL17294700 | 0.70 | CHRM2 (0.57) | CCR1CHRM2CHRM1CHRM3 | |
| SCHEMBL17294698 | 0.70 | CHRM2 (0.57) | CCR1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148518-B1 | NOVEL COMPOUNDS AS ANTI-TUBERCULAR AGENTS | SPHAERA PHARMA PRIVATE LTD (IN) | 2022-11-30 | — | — | EP | disclosed |