Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17294690 | 0.81 | BACE1 (0.56) | CCR1ALDH1A1 | |
| SCHEMBL17301751 | 0.81 | BACE1 (0.56) | CCR1ALDH1A1 | |
| SCHEMBL17294691 | 0.81 | BACE1 (0.56) | CCR1ALDH1A1 | |
| SCHEMBL14050745 | 0.81 | CCR1 (0.68) | CCR1POLBTSHRCYP3A4CYP2C19 | |
| SCHEMBL19049037 | 0.80 | CCR1 (0.55) | CCR1C3AR1 | |
| SCHEMBL6437249 | 0.78 | POLB (0.62) | CCR1POLBTSHRMAPTALDH1A1 | |
| SCHEMBL6858432 | 0.76 | CTSL (0.66) | — | |
| Oxalic Acid SCHEMBL7729520 | 0.75 | CCR1 (0.58) | CCR1TSHRCYP3A4C3AR1CYP2D6 | |
| Oxalic Acid SCHEMBL7729513 | 0.75 | CCR1 (0.58) | CCR1TSHRCYP3A4C3AR1CYP2D6 | |
| SCHEMBL7729558 | 0.74 | CCR1 (0.60) | CCR1TSHRCYP3A4C3AR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148518-B1 | NOVEL COMPOUNDS AS ANTI-TUBERCULAR AGENTS | SPHAERA PHARMA PRIVATE LTD (IN) | 2022-11-30 | — | — | EP | disclosed |